منابع مشابه
Hexokinases and cardioprotection.
As mediators of the first enzymatic step in glucose metabolism, hexokinases (HKs) orchestrate a variety of catabolic and anabolic uses of glucose, regulate antioxidant power by generating NADPH for glutathione reduction, and modulate cell death processes by directly interacting with the voltage-dependent anion channel (VDAC), a regulatory component of the mitochondrial permeability transition p...
متن کاملHexokinases and glucokinases.
Johnson, P. M., Cheng, H. M., Molloy, C. M., Stern, C. M. M. & Slade, M. B. ( 198 1) Am. J . Heprod. Immunol. 1,246-254 Travers, P. & Bodmer, W. ( 1984) hi. J . C’uncer 33,633-64 1 McLaughlin, P. J., Twist, A,, Evans, C. C. & Johnson, P. M. (1984) J . C‘lin. I’uthol. 37,826-828 Tucker, D. F. & Milford Ward, A. ( 1988) in C‘uncer Diugnosis in vitro itsing monoclonal antibodies (Kupchik, H. 2.. e...
متن کاملProduct inhibition of the hexokinases.
ADP3and ADPMg caused mixed inhibition of purified yeast hexokinase isoenzymes and ascites tumor hexokinases I and II when ATPMg is the varied substrate. Since exchange between ADPMg and ATPMg is observed under steady state conditions in which free glucose-6-P is not available for reaction, the effect of ADPMg on V,,, must result from its reaction at the ADP product site of the enzyme. glucose-6...
متن کاملPerspectives in innate and acquired cardioprotection: cardioprotection acquired through exercise.
Emerging evidence indicates that exercise training can provide significant protection against myocardial ischemia-reperfusion injury. In this brief review, we provide a synthesis of current literature in the field and summarize the findings to date. Our intent is to identify the unique elements of cardioprotection acquired by exercise, and to illustrate what distinguishes this physiological acq...
متن کاملExercise, Antioxidants, and Cardioprotection
Scott K. Powers, Ph.D., Ed.D. Professor Department of Exercise and Sport Sciences and Department of Physiology University of Florida Gainesville, Florida In addition to the cardioprotective effects of regular exercise, there is also a growing interest in nutritional antioxidant supplementation as a strategy to protect the heart during a heart attack. Indeed, the role that dietary antioxidants p...
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ژورنال
عنوان ژورنال: Journal of Molecular and Cellular Cardiology
سال: 2015
ISSN: 0022-2828
DOI: 10.1016/j.yjmcc.2014.09.020